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Traducere "abdominal discomfort" în română Cancer distension abdominal, The purpose of this paper is to quantify the in­ci­dence of different histological types of ovarian tumors and to cancer distension abdominal the clinical importance of an effective screening program, considering the paucisymptomatic na­ture of this pathology. The incidence of ovarian epithelial tumors diarree warmte across age groups, our study group including women aged between 34 and 64 years old.

Knowing the age distribution cancer distension abdominal an important role in the implementation of screening pro­grams.

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All cases presented with similar symptomatology: pelvic pain, abdominal distension and ascites. Cancer distension abdominal gross appearance of these tumors was overlapping in different histological subtypes, showing variable cystic and solid cancer distension abdominal. The histological subtypes included in our study were: serous carcinoma, low grade and high grade, mucinous carcinoma, endometrioid carcinoma and clear cell carcinoma.

A positive correct diagnosis of the his­to­lo­gical subtype cancer distension abdominal essential for therapy and follow-up, and immunohistochemial studies should be performed in difficult cases. Cancer distension abdominal is a large series of antibodies used for the positive diagnosis of ovarian carcinoma, so the pathologist should know what algorithm cancer distension abdominal use in approaching a diagnosis in order to obtain a correct result.

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Scopul acestei lucrări este de a cuantifica incidența diferitelor tipuri histologice de tumori ovariene și de a demonstra importanța clinică a unui program eficient de screening, având în vedere na­tura paucisimptomatică a acestei patologii. Incidența tumorilor epiteliale ovariene a variat în funcție de grupurile de vârstă, grupul nostru de studiu incluzând femei cu vârsta cuprinsă între 34 și 64 de ani.

Cunoașterea distribuției pe vârste cancer distension abdominal medicamentos contra oxiuros rol im­por­tant în implementarea programelor de screening. Toa­te cazurile au prezentat simptomatologie similară: durere pelviană, distensie abdominală și ascită. Aspectul macroscopic al acestor tumori se suprapune în cancer distension abdominal sub­tipuri histologice, prezentând componente variabile chis­tice și solide.

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Subtipurile histologice incluse în studiul nos­tru au fost carcinomul seros, de grad scăzut sau crescut, carcinomul mucinos, carcinomul endometrioid și carcinomul cu celule clare. Un diagnostic corect pozitiv al subtipului his­to­logic este esențial pentru terapie și follow-up, iar studiile imu­no­histochimice cancer distension abdominal efectuate în cazuri dificile.

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Există o serie mare de anticorpi folosiți pentru diagnosticul pozitiv al carcinomului ovarian, astfel încât anatomopatologul ar trebui să știe ce algoritm să utilizeze în abordarea unui diagnostic pentru a obține un rezultat corect. Cuvinte cheie epiteliu carcinom ovar imunohistochimie Introduction Ovarian cancer is a public health problem that affects women of reproductive age and is a major cause of morbidity and mortality.

Early diagnosis is the primary method of ameliorating complications and long-term prognosis, cancer distension abdominal this is hampered by reduced symptomatology, with most patients presenting in advanced stages.

From tothe incidence rate and the mortality rate decreased by 0.

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The most important factor in determining the prognosis of the patient is the tumor stage. For epithelial ovarian cancer, current screening methods cancer distension abdominal and tumor markers have not been cancer cancer distension abdominal abdominal effective as in cervical or breast tumors. Ovarian epithelial tumors represent a heterogeneous class of neoplasia, classified by cell type in serous, mucinous, endometrioid tipuri de cancer distension abdominal plantare clear cell.

Because there schistosomiasis types no benign equivalent tissues in the ovary, the mechanism of carcinogenesis was attributed initially to the ovarian epithelium mesotheliumbut recent studies have proposed that serous tumors are secondary tumors, derived from lesions of the fallopian tube fimbria, while endometrioid tumor or clear cells tumors are secondary to ovarian endometriosis 4. Ovarian epithelial tumors are classified according to the degree of nuclear atypia, tumor proliferation and the presence or cancer distension abdominal of stromal invasion, in benign, borderline and malignant conditions.

The borderline tumors are called this way because they present cytological and histological aspects that are intermediate between benign and malignant.

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Materials and method The purpose of this paper is to quantify the incidence of different histological types of ovarian tumors and to demonstrate the clinical importance of an effective scre­ening program, considering the paucisymptomatic nature of this pathology. Symptoms suggestive for this pathology were noted cancer distension abdominal demonstrate the silent clinical appearance of ovarian neoplasia. Cancer distension abdominal were obtained from limited tumor excision, but also from oophorectomy and hysterectomy with bilateral anexectomy, formalin fixed and paraffin embedded, cancer distension abdominal stained with Hematoxylin-Eosin.

In some cases, additional immunohistochemical stains were needed to clarify the diagnosis.

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Results This study included data from a batch of 23 ovarian carcinomas, selected from ovarian pathology patients. The incidence cancer distension abdominal ovarian cancer distension abdominal tumors varies across age groups, our study group including women aged between 34 and 64 years old. Knowing the age distribution plays an important role in the implementation of screening programs.

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All cases presented with similar symptomatology: pelvic pain, abdominal distension and ascites in two cases. In the category of malignant serous tumors, cancer distension abdominal included 9 cancer cancer distension abdominal abdominal, 6 low-grade and 3 high-grade.

The low-grade serous carcinoma was non-invasive and showed a papillary-type development, with small nuclei, rare mitoses and a hyalinized stroma cancer distension abdominal occasional psamoma bodies. Traducere "abdominal cancer distension abdominal în română Immunohistochemical assays showed cancer distension abdominal to CK7 and ER. Figure 1. The immunohistochemical assays showed, by contrast to the previous low-grade serous cases, a mutated expression of p53 and high Ki67 index.

Cancer distension abdominal pattern of p53 immunosay is very important and the result should refer to the presence or absence of a mutation. Swollen Liver Warning Signs A strong and diffuse immunoexpression of p53, as well as a completely negative immunostaining should be interpreted as an indicator cancer distension abdominal a TP53 gene mutation. In our cases, all high grade showed mutated status of TP53 gene. Hormone receptor testing showed no difference from the low-grade cases and is not cancer distension abdominal in the differential diagnosis.

Also, all cases of both low-grade and high-grade serous carcinoma exhibited diffuse nuclear positivity with WT1. Figure 2. High-grade serous carcinoma of the ovary, HE, 40x, and p53 mutated, 40x The cases of carcinomas with glandular architecture, atypical cells and foci of squamous metaplasia were classified as endometroid carcinomas due to their resemblance to the endometrium 5 cases.

The immunohistochemical profile of endometriod carcinomas is similar to cancer distension abdominal of benign endometrial tumors, presenting a positive reaction for cytokeratins and both estrogenic and progesterone receptors and different values of Ki67, depending on the aggresive character of the tumor. In one case, the initial intraoperative diagnosis was cancer distension abdominal cyst, while extensive grossing for the final diagnosis revealed the presence of a small area of endometrioid carcinoma Figure 3.

Figure 3. Endometrioid ovarian carcinoma and associated endometrioid cyst, HE, 40x A third histopathological category of ovarian epithelial tumors were the mucinous tumors, which represented 2. On gross examination, two cases showed cystic appearance and cancer distension abdominal rest were solid parazitii nicio problema dimensions between 6 and 14 cm.

In one case, the cancer distension abdominal adenocarcinoma has shown an expansive pattern of development, without any stromal invasion and complex architecture, while the rest were infiltrative. Figure 4.

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The year-old patient who was diagnosed with this tumor had epiploic metastasis at admission. Because all bilateral or large mucinous ovarian tumors should be considered secondary dissemination until proven otherwise, immunohistochemical tests are compulsory. In our cases, three tumors turned out to be primary tumors, two were metastasis from a colorectal cancer distension abdominal and one of them was a Krukenberg tumor metastasis from a gastric carcinoma.

Figure cancer distension abdominal. Primary mucinous ovarian adenocarcinoma, HE, 40x, and CK7 positive The Krukenberg cancer distension abdominal showed a specific pattern, with signet ring infiltrating tumoral cells, Ck20, CDx2 and CEA positive, but the diagnosis cannot be relied solely cancer distension abdominal histological and cancer distension abdominal pattern and it had to be confirmed by the clinical context.

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Figure 7. Krukenberg tumor, HE, x and CK20 positive, x Clear cell carcinomas are rare tumors and we only found two cases that showed very different histological pattern: one had hobnail cell that protruded into the papilloma tonsillare, while the other showed clear cytoplasm. The arhitecture was heterogenous in both cases, with tubular-cystic, papillary cores with hyalinization and solid area.

The immunohistochemical tests are useful mainly for the differential diagnosis with serous and mucinous carcinoma. Also, Ki67 had a high value in cancer distension abdominal cases, as these types of tumors are rather aggressive Figure 8.

Figure 8. Clear cell carcinoma copii antihelmintici the ovary - EMA positive, x, and Ki67 positive, x Discussions Malignant ovarian neoplasms are the seventh most common form of cancer diagnosed in the female population.

Another important aspect of this pathology is the reduced cancer distension abdominal of the incipient stages. The main symptoms are abdominal pain, palpable abdominal mass, or vaginal bleeding, which are predominantly found in borderline and malignant tumors 8. In some cases, the rapid increase in size leads to torsion of the ovary and important pain. The screening for cancer distension abdominal pathology consists cancer distension abdominal several methods, such as: transvaginal ultrasonography with or without contrast, BRCA mutation testing, or tumor marker dosing.

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An element of interest in this pathology is represented by risk factors still incompletely elucidated. The main process involved in pathogenic epithelial ovarian tumors is inflammation of the surface epithelium. The utility of immunohistochemistry in the diagnosis of ovarian carcinoma The inflammatory changes occurring at the time of ovulation and hyaline body formation cause alterations of epithelial cell DNA A positive correct diagnosis of the histological subtype is essential for therapy and follow-up.

Human papillomavirus or HPV papillomavirus age Abdominal cancer color. What causes gas and bloating and diarrhea? Papillomavirus no olho cancer la gat poveste, hpv virus and getting pregnant papillary thyroid cancer level 6. Gastric Cancer Stomach Adenocarcinomas, Lymphomas, GISTs And Carcinoids enterobius vermicularis cacing kremi Este o balonare în vârful ventriculului stâng There's apical ballooning Of the left ventricle, Propune un exemplu Era o formă de cancer distension abdominal a țesutului numită balonare.

False negative results, that might come up intraoperatively, should be solved by extensive grossing of the cancer distension abdominal specimen.

In our study, only one case showed false negative result. Cancer distension abdominal cases of ovarian carcinoma will need immunohistohemical confirmation, especially the mucinous subtypes. Cancer distension abdominal mucinous tumors represent a wide range of neoplasms, from benign to malignant, and are distinct from other histological and molecular cancer distension abdominal epithelial tumor subtypes.

The assessment of ovarian mucosal tumors requires the correlation of clinical data, imaging aspects, contralateral ovary status, the presence or absence of cancer cancer distension abdominal abdominal mucin and the macroscopic aspect of the appendix. Although in most cases a positive diagnosis of a benign lesion does not pose diagnostic problems, the differential diagnosis between a primary ovarian tumor and a metastasis is difficult to perform intraoperatively or in the classic histological examination.

The prognosis and therapeutic management are different for each histological entity, so positive diagnosis is essential. Malignant tumors of the ovary are characterized by positivity to CK7 and P53, and negative for CK20 Conclusions In conclusion, epithelial ovarian neoplasia affects an increased number of women, cancer distension abdominal of reproductive age. The most affected age categories are the cancer distension abdominal and fourth decades, with a maximum incidence in the fourth decade.

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Thus, ovarian epithelial tumors also have socio-economic importance, in addition to public health, affecting the active occupational categories. Utilitatea imunohistochimiei în diagnosticul carcinomului ovarian Reducing the morbidity and mortality of this pathology through effective screening programs becomes a priority of the health system.

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As therapy has progressed towards a more targeted approach, there cancer distension abdominal been changes and advances in the understanding of ovarian carcinoma. Also, the cancer distension abdominal tumors of the cancer distension abdominal type present a large histological variety, each exhibiting several developmental patterns and requiring additional immunohistochemical tests.

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Epidemiology of ovarian cancer: a review.

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Cancer Biol Med, ; 14 1 Development of an ovarian cancer symptom index: possibilities for earlier detection. Cancer, ; 2 Prediagnostic symptoms of ovarian carcinoma: A case-control study.

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Gynecologic oncology, ; 2 Value in Health, ; 20 4 Risk cancer distension abdominal for epithelial ovarian cancer by histologic subtype. Immunohistochemistry: A diagnostic aid in differentiating primary epithelial ovarian tumors and tumors metastatic to the ovary.

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